Showing: 1 - 10 of 12 RESULTS
GABAA and GABAC Receptors

(1) Does proteomics identify expressed proteins resembling those of embryonic stem and iPS cells? Pluripotency is definitely defined by manifestation of transcription factors, signaling proteins, and developmental proteins much like those in well-established pluripotent stem cells; (2) Do proteins indicated in splenic stem cells confirm the multi-lineage target cells into which these stem cells already have been shown to differentiate? (3) In keeping with the evolutionary part of stem cells to replace hurt or diseased cells, do splenic stem cells upregulate gene manifestation as a result of pathology in another organ? More specifically, in an animal model of type 1 diabetes, does pancreatic disease during the pre-diabetic phase result in the spleen to upregulate stem cell proteins and/or the number of stem cells potentially available for migration and repair of pancreatic function? (4) Given the carcinogenic risk of introducing stem cells harvested from embryos or iPS, do CD45- stem cells communicate proteins that overlap with those of the signature genes of HOX11+ T cell leukemias? Assessment between these two populations may reveal proteins necessary to target for prevention and treatment of this leukemia

(1) Does proteomics identify expressed proteins resembling those of embryonic stem and iPS cells? Pluripotency is definitely defined by manifestation of transcription factors, signaling proteins, …

GABAA and GABAC Receptors

In addition we found that efficacy of fasudil was best with doses of 10 mg/kg; however in the clinical trial of fasudil the dose used was 60 mg which equates to roughly 1 mg/kg and this was administered intravenously whereas the most frequent route of delivery was intraperitoneal in the preclinical literature

In addition we found that efficacy of fasudil was best with doses of 10 mg/kg; however in the clinical trial of fasudil the dose used …